pentobarbital will lower the level or effect of artemether/lumefantrine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration with robust CYP3A4 inducers may lead to lowered serum concentrations and lack of antimalarial efficacyCheck Carefully (1)pentobarbital will raise the stage or impact… Read More